About BTB/POZ domain-containing protein KCTD11
BTB/POZ domain-containing protein KCTD11 (KCTD11) is a protein
from Homo sapiens identified by UniProt accession
Q693B1, 232 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | BTB/POZ domain-containing protein KCTD11 |
|---|
| UniProt accession | Q693B1 |
|---|
| Gene | KCTD11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 232 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- hypothyroidism · score 0.11
- Hashimoto's thyroiditis · score 0.11
- neutrophil count · score 0.10
- lymphocyte count · score 0.09
- thyroid disease · score 0.09
- leukocyte count · score 0.09
- myeloid white cell count · score 0.09
- monocyte percentage of leukocytes · score 0.09
- Blackfan-Diamond anemia · score 0.08
- type 1 diabetes mellitus · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q693B1-F1 | alphafold | PREDICTED | 84.22 | — |
Amino-acid sequence (232 residues)
MLGAMFRAGT PMPPNLNSQG GGHYFIDRDG KAFRHILNFL RLGRLDLPRG YGETALLRAE ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH HYELSSVQVD TFRANLFCTD SECLGALRAR FGVASGDRAE GSPHFHLEWA PRPVELPEVE YGRLGLQPLW TGGPGERREV VGTPSFLEEV LRVALEHGFR LDSVFPDPED LLNSRSLRFV RH
Explore BTB/POZ domain-containing protein KCTD11 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets