About CWF19-like protein 1
CWF19-like protein 1 (CWF19L1) is a protein
from Homo sapiens identified by UniProt accession
Q69YN2, 538 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | CWF19-like protein 1 |
|---|
| UniProt accession | Q69YN2 |
|---|
| Gene | CWF19L1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 538 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- autosomal recessive spinocerebellar ataxia 17 · score 0.76
- triglyceride measurement · score 0.26
- Intellectual disability · score 0.26
- genetic disorder · score 0.19
- self reported educational attainment · score 0.19
- serum alanine aminotransferase measurement · score 0.18
- total cholesterol measurement · score 0.18
- type 2 diabetes mellitus · score 0.18
- intelligence · score 0.17
- low density lipoprotein cholesterol measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q69YN2-F1 | alphafold | PREDICTED | 83.37 | — |
Amino-acid sequence (538 residues)
MAQKPLRLLA CGDVEGKFDI LFNRVQAIQK KSGNFDLLLC VGNFFGSTQD AEWEEYKTGI KKAPIQTYVL GANNQETVKY FQDADGCELA ENITYLGRKG IFTGSSGLQI VYLSGTESLN EPVPGYSFSP KDVSSLRMML CTTSQFKGVD ILLTSPWPKC VGNFGNSSGE VDTKKCGSAL VSSLATGLKP RYHFAALEKT YYERLPYRNH IILQENAQHA TRFIALANVG NPEKKKYLYA FSIVPMKLMD AAELVKQPPD VTENPYRKSG QEASIGKQIL APVEESACQF FFDLNEKQGR KRSSTGRDSK SSPHPKQPRK PPQPPGPCWF CLASPEVEKH LVVNIGTHCY LALAKGGLSD DHVLILPIGH YQSVVELSAE VVEEVEKYKA TLRRFFKSRG KWCVVFERNY KSHHLQLQVI PVPISCSTTD DIKDAFITQA QEQQIELLEI PEHSDIKQIA QPGAAYFYVE LDTGEKLFHR IKKNFPLQFG REVLASEAIL NVPDKSDWRQ CQISKEDEET LARRFRKDFE PYDFTLDD
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