About Ankyrin repeat domain-containing protein 40
Ankyrin repeat domain-containing protein 40 (ANKRD40) is a protein
from Homo sapiens identified by UniProt accession
Q6AI12, 368 residues long.
MolForge cross-references it against 0 known binders and
7 disease associations.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 40 |
|---|
| UniProt accession | Q6AI12 |
|---|
| Gene | ANKRD40 |
|---|
| Organism | Homo sapiens |
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| Length | 368 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (7)
Diseases linked to this target (Open Targets).
- bilirubin measurement · score 0.06
- heel bone mineral density · score 0.05
- urate measurement · score 0.04
- bone density · score 0.04
- neoplasm · score 0.01
- autism · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6AI12-F1 | alphafold | PREDICTED | 68.48 | — |
Amino-acid sequence (368 residues)
MNALLEQKEQ QERLREAAAL GDIREVQKLV ESGVDVNSQN EVNGWTCLHW ACKRNHGQVV SYLLKSGADK EILTTKGEMP VQLTSRREIR KIMGVEEEDD DDDDDDNLPQ LKKESELPFV PNYLANPAFP FIYTPTAEDS AQMQNGGPST PPASPPADGS PPLLPPGEPP LLGTFPRDHT SLALVQNGDV SAPSAILRTP ESTKPGPVCQ PPVSQSRSLF SSVPSKPPMS LEPQNGTYAG PAPAFQPFFF TGAFPFNMQE LVLKVRIQNP SLRENDFIEI ELDRQELTYQ ELLRVCCCEL GVNPDQVEKI RKLPNTLLRK DKDVARLQDF QELELVLMIS ENNFLFRNAA STLTERPCYN RRASKLTY
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