About Bridge-like lipid transfer protein family member 3A
Bridge-like lipid transfer protein family member 3A (BLTP3A) is a protein
from Homo sapiens identified by UniProt accession
Q6BDS2, 1440 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Bridge-like lipid transfer protein family member 3A |
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| UniProt accession | Q6BDS2 |
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| Gene | BLTP3A |
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| Organism | Homo sapiens |
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| Length | 1440 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (100)
Diseases linked to this target (Open Targets).
- body height · score 0.31
- high density lipoprotein cholesterol measurement · score 0.29
- body mass index · score 0.29
- systemic lupus erythematosus · score 0.27
- physical activity measurement · score 0.26
- waist circumference · score 0.25
- sex hormone-binding globulin measurement · score 0.24
- platelet count · score 0.24
- Red cell distribution width · score 0.22
- prostate carcinoma · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6BDS2-F1 | alphafold | PREDICTED | 66.18 | — |
Amino-acid sequence (1440 residues)
MAGIIKKQIL KHLSRFTKNL SPDKINLSTL KGEGQLTNLE LDEEVLQNVL ELPTWLAITR VYCNRASIRI QWTKLKTHPI CLCLDKVEVE MKTCEDPRPP NGQSPIALAS GQSEYGFAEK VVEGMFIIVN SITIKIHSKA FHASFELWQL QGYSVNPNWQ QSDLRLTRIT DPCRGEVLTF KEITWQTLRI EADATDNGDQ DPVTTPLRLI TNQGRIQIAL KRRTKDCNVI SSKLMFLLDD LLWVLTDSQL KAMMKYAESL SEAMEKSAHQ RKSLAPEPVQ ITPPAPSAQQ SWAQAFGGSQ GNSNSSSSRL SQYFEKFDVK ESSYHLLISR LDLHICDDSQ SREPGVSANR LMGGAMQLTF RKMAFDYYPF HWAGDSCKHW VRHCEAMETR GQWAQKLVME FQSKMEKWHE ETGLKPPWHL GVDSLFRRKA DSLSSPRKNP LERSPSQGRQ PAFQPPAWNR LRSSCMVVRV DDLDIHQVST AGQPSKKPST LLSCSRKLHN LPTQVSAIHI EFTEYYFPDN QELPVPCPNL YIQLNGLTFT MDPVSLLWGN LFCLDLYRSL EQFKAIYKLE DSSQKDEHLD IRLDAFWLKV SFPLEKRERA ELHRPQALVF SASGMIATNT RHAPHCSCSD LQSLFRGFAA AEFFHSNYDH FPKVPGGFSL LHMLFLHHAF QMDSCLPQPN TLPPQRPKAS WDLWSVHFTQ ISLDFEGTEN FKGHTLNFVA PFPLSIWACL PLRWQQAQAR KLLLASEGRL KPSASFGSPV QSEALAPDSM SHPRSKTEHD LKSLSGLTEV MEILKEGSSG MDNKGPLTEL EDVADVHMLV HSPAHVRVRL DHYQYLALLR LKEVLQRLQE QLTKDTESMT GSPLQNQTAC IGVLFPSAEV ALLMHPAPGA VDADSAGSDS TSLVDSELSP SEDRELKSDA SSDQGPASPE KVLEESSIEN QDVSQERPHS NGELQDSGPL AQQLAGKGHE AVESLQAKKL SRTQASSSPA ALKPPAGRET AVNGQGELIP LKNIEGELSS AIHMTKDATK EALHATMDLT KEAVSLTKDA FSLGRDRMTS TMHKMLSLPP AKEPMAKTDE GVAAPVSGGA ARLRFFSMKR TVSQQSFDGV SLDSSGPEDR ISVDSDGSDS FVMLLESESG PESVPPGSLS NVSDNAGVQG SPLVNNYGQG SPAANSSVSP SGEDLIFHPV SVLVLKVNEV SFGIEVRGED LTVALQAEEL TLQQLGTVGL WQFLHGQCPG TCFQESSTLK TGHIRPAVGL RFEVGPGAAV HSPLASQNGF LHLLLHGCDL ELLTSVLSGL GPFLEDEEIP VVVPMQIELL NSSITLKDDI PPIYPTSPGP IPITLAMEHV VLKRSDDGVF HIGAAAQDKP SAEVLKSEKR QPPKEQVFLV PTGEVFEQQV KELPILQKEL IETKQALANA NQDKEKLLQE IRKYNPFFEL
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