About Multiple C2 and transmembrane domain-containing protein 1
Multiple C2 and transmembrane domain-containing protein 1 (MCTP1) is a protein
from Homo sapiens identified by UniProt accession
Q6DN14, 999 residues long.
MolForge cross-references it against 0 known binders and
95 disease associations.
Target properties
| Protein name | Multiple C2 and transmembrane domain-containing protein 1 |
|---|
| UniProt accession | Q6DN14 |
|---|
| Gene | MCTP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 999 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (95)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- smoking initiation · score 0.30
- body mass index · score 0.29
- smoking status measurement · score 0.27
- amyloid-beta measurement · score 0.27
- body fat percentage · score 0.24
- smoking behavior · score 0.20
- attention deficit hyperactivity disorder · score 0.14
- antisocial behaviour measurement · score 0.14
- substance abuse · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6DN14-F1 | alphafold | PREDICTED | 64.71 | — |
Amino-acid sequence (999 residues)
MEPRAAAAGE PEPPAASSSF QARLWKNLQL GVGRSKGGGG GRAGGPERRT ADTPSPSPPP PVGTGNAPAR GSGAGSRWSG FKKRKQVLDR VFSSSQPNLC CSSPEPLEPG GAGRAEQGST LRRRIREHLL PAVKGPAAAS GAAGGTPPGG RSPDSAPSSS SASSSLSSSP QPPPRGDRAR DEGARRQGPG AHLCHQKSSS LPGTACLEQL LEPPPPPAEP ARSPAESRAP ETGEEHGSSQ KIINTAGTSN AEVPLADPGM YQLDITLRRG QSLAARDRGG TSDPYVKFKI GGKEVFRSKI IHKNLNPVWE EKACILVDHL REPLYIKVFD YDFGLQDDFM GSAFLDLTQL ELNRPTDVTL TLKDPHYPDH DLGIILLSVI LTPKEGESRD VTMLMRKSWK RSSKELSENE VVGSYFSVKS LFWRTCGRPA LPVLGFCRAE LQNPYCKNVQ FQTQSLRLSD LHRKSHLWRG IVSITLIEGR DLKAMDSNGL SDPYVKFRLG HQKYKSKIMP KTLNPQWREQ FDFHLYEERG GVIDITAWDK DAGKRDDFIG RCQVDLSALS REQTHKLELQ LEEGEGHLVL LVTLTASATV SISDLSVNSL EDQKEREEIL KRYSPLRIFH NLKDVGFLQV KVIRAEGLMA ADVTGKSDPF CVVELNNDRL LTHTVYKNLN PEWNKVFTFN IKDIHSVLEV TVYDEDRDRS ADFLGKVAIP LLSIQNGEQK AYVLKNKQLT GPTKGVIYLE IDVIFNAVKA SLRTLIPKEQ KYIEEENRLS KQLLLRNFIR MKRCVMVLVN AAYYVNSCFD WDSPPRSLAA FVLFLFVVWN FELYMIPLVL LLLLTWNYFL IISGKDNRQR DTVVEDMLED EEEEDDKDDK DSEKKGFINK IYAIQEVCVS VQNILDEVAS FGERIKNTFN WTVPFLSWLA IVALCVFTAI LYCIPLRYIV LVWGINKFTK KLRSPYAIDN NELLDFLSRV PSDVQVVQYQ ELKPDPSHSP YKRKKNNLG
Explore Multiple C2 and transmembrane domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets