Fc receptor-like protein 6 (FCRL6)

About Fc receptor-like protein 6

Fc receptor-like protein 6 (FCRL6) is a protein from Homo sapiens identified by UniProt accession Q6DN72, 434 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Fc receptor-like protein 6
UniProt accession	Q6DN72
Gene	FCRL6
Organism	Homo sapiens
Length	434 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

C-reactive protein measurement · score 0.05
Rheumatoid arthritis · score 0.04
neurofibrillary tangles measurement · score 0.03
neoplasm · score 0.02
protein measurement · score 0.02
type 1 diabetes mellitus · score 0.01
type 2 diabetes mellitus · score 0.01
chronic periodontitis · score 0.01
HIV-1 infection · score 0.01
chronic lymphocytic leukemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6DN72-F1	alphafold	PREDICTED	76.22	—

Amino-acid sequence (434 residues)

MLLWTAVLLF VPCVGKTVWL YLQAWPNPVF EGDALTLRCQ GWKNTPLSQV KFYRDGKFLH FSKENQTLSM GAATVQSRGQ YSCSGQVMYI PQTFTQTSET AMVQVQELFP PPVLSAIPSP EPREGSLVTL RCQTKLHPLR SALRLLFSFH KDGHTLQDRG PHPELCIPGA KEGDSGLYWC EVAPEGGQVQ KQSPQLEVRV QAPVSRPVLT LHHGPADPAV GDMVQLLCEA QRGSPPILYS FYLDEKIVGN HSAPCGGTTS LLFPVKSEQD AGNYSCEAEN SVSRERSEPK KLSLKGSQVL FTPASNWLVP WLPASLLGLM VIAAALLVYV RSWRKAGPLP SQIPPTAPGG EQCPLYANVH HQKGKDEGVV YSVVHRTSKR SEARSAEFTV GRKDSSIICA EVRCLQPSEV SSTEVNMRSR TLQEPLSDCE EVLC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards