Interleukin-31 (IL31)

Homo sapiens — UniProt Q6EBC2

Gene: IL31Homo sapiensSwissProt reviewed

About Interleukin-31

Interleukin-31 (IL31) is a protein from Homo sapiens identified by UniProt accession Q6EBC2, 164 residues long. MolForge cross-references it against 0 known binders and 334 disease associations.

Target properties

Protein nameInterleukin-31
UniProt accessionQ6EBC2
GeneIL31
OrganismHomo sapiens
Length164 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (334)

Diseases linked to this target (Open Targets).

  • Cutaneous T-cell lymphoma · score 0.11
  • psoriasis · score 0.10
  • allergic rhinitis · score 0.10
  • neoplasm · score 0.10
  • self reported educational attainment · score 0.09
  • Pruritus · score 0.09
  • Eczematoid dermatitis · score 0.09
  • gonorrhea · score 0.08
  • systemic scleroderma · score 0.08
  • Dilated cardiomyopathy · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6EBC2-F1alphafoldPREDICTED79.34—

Amino-acid sequence (164 residues)

MASHSGPSTS VLFLFCCLGG WLASHTLPVR LLRPSDDVQK IVEELQSLSK MLLKDVEEEK GVLVSQNYTL PCLSPDAQPP NNIHSPAIRA YLKTIRQLDN KSVIDEIIEH LDKLIFQDAP ETNISVPTDT HECKRFILTI SQQFSECMDL ALKSLTSGAQ QATT

Explore Interleukin-31 with MolForge

Find binders, run structure-based screening, and map this target across diseases and approved drugs with our AI-powered platform.

Browse all targets

Quick facts

UniProtQ6EBC2
GeneIL31
OrganismHomo sapiens
Length164
Binders0
Diseases334
View on UniProt