About Zinc finger protein 470
Zinc finger protein 470 (ZNF470) is a protein
from Homo sapiens identified by UniProt accession
Q6ECI4, 717 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Zinc finger protein 470 |
|---|
| UniProt accession | Q6ECI4 |
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| Gene | ZNF470 |
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| Organism | Homo sapiens |
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| Length | 717 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (15)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.37
- apolipoprotein B measurement · score 0.27
- low density lipoprotein cholesterol measurement · score 0.20
- neurodegenerative disease · score 0.20
- pancreatic adenocarcinoma · score 0.14
- lymphocyte count · score 0.09
- body height · score 0.02
- substance abuse · score 0.02
- attention deficit hyperactivity disorder · score 0.02
- antisocial behaviour measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ECI4-F1 | alphafold | PREDICTED | 71.63 | — |
Amino-acid sequence (717 residues)
MKSQEEVEVA GIKLCKAMSL GSVTFTDVAI DFSQDEWEWL NLAQRSLYKK VMLENYRNLV SVGLCISKPD VISLLEQEKD PWVIKGGMNR GLCPDLECVW VTKSLSLNQD IYEEKLPPAI IMERLKSYDL ECSTLGKNWK CEDLFERELV NQKTHFRQET ITHIDTLIEK RDHSNKSGTV FHLNTLSYIK QIFPMEERIF NFHTDKKSLK THSVVKKHKQ DRGEKKLLKC NDCEKIFSKI STLTLHQRIH TGEKPYECIE CGKAFSQSAH LAQHQRIHTG EKPFECTECG KAFSQNAHLV QHQRVHTGEK PYQCKQCNKA FSQLAHLAQH QRVHTGEKPY ECIECGKAFS DCSSLAHHRR IHTGKRPYEC IDCGKAFRQN ASLIRHRRYY HTGEKPFDCI DCGKAFTDHI GLIQHKRTHT GERPYKCNVC GKAFSHGSSL TVHQRIHTGE KPYECNICEK AFSHRGSLTL HQRVHTGEKP YECKECGKAF RQSTHLAHHQ RIHTGEKPYE CKECSKTFSQ NAHLAQHQKI HTGEKPYECK ECGKAFSQIA HLVQHQRVHT GEKPYECIEC GKAFSDGSYL VQHQRLHSGK RPYECLECGK AFRQRASLIC HQRCHTGEKP YECNVCGKAF SHRKSLTLHQ RIHTGEKPYE CKECSKAFSQ VAHLTLHKRI HTGERPYECK ECGKAFRQSV HLAHHQRIHT GESSVILSSA LPYHQVL
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