Uncharacterized protein C22orf42 (C22orf42)

About Uncharacterized protein C22orf42

Uncharacterized protein C22orf42 (C22orf42) is a protein from Homo sapiens identified by UniProt accession Q6IC83, 251 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Uncharacterized protein C22orf42
UniProt accession	Q6IC83
Gene	C22orf42
Organism	Homo sapiens
Length	251 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

linoleic acid measurement · score 0.20
visual perception measurement · score 0.20
HbA1c measurement · score 0.07
anti-chlamydia trachomatis antibody measurement · score 0.07
1,5 anhydroglucitol measurement · score 0.05
glucose tolerance test · score 0.04
urate measurement · score 0.04
type 2 diabetes mellitus · score 0.04
glucagon-like peptide-1 measurement · score 0.03
glucose-dependent insulinotropic peptide measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6IC83-F1	alphafold	PREDICTED	51.65	—

Amino-acid sequence (251 residues)

MGSKLTCCLG PSGGLNCDCC RPDVGPCHEC EIPETVAATA PASTTAKPAK LDLKAKKAQL MQYLSLPKTP KMLKMSKGLD ARSKRWLKII WRRHGIWPLE NIGPTEDVQA SAHGGVEENM TSDIEIPEAK HDHRPTEDVQ VSAHGGVEEN ITSDIEISEA KHDHHLVEDL SESLSVCLED FMTSDLSESL SVSLEDFMTS GLSESLSVSL EDLMTPEMAK ERYEDYLCWV KMARSRLNEP ISSQVLGLLR L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards