About Sesquipedalian-2
Sesquipedalian-2 (PHETA2) is a protein
from Homo sapiens identified by UniProt accession
Q6ICB4, 259 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Sesquipedalian-2 |
|---|
| UniProt accession | Q6ICB4 |
|---|
| Gene | PHETA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 259 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- serum non-albumin protein measurement · score 0.13
- leukocyte count · score 0.12
- schizophrenia · score 0.10
- platelet component distribution width · score 0.10
- autism spectrum disorder · score 0.09
- eosinophil count · score 0.08
- bipolar disorder · score 0.08
- Tourette syndrome · score 0.07
- unipolar depression · score 0.07
- mathematical ability · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ICB4-F1 | alphafold | PREDICTED | 75.86 | — |
Amino-acid sequence (259 residues)
MKLNERSVAH YALSDSPADH MGFLRTWGGP GTPPTPSGTG RRCWFVLKGN LLFSFESREG RAPLSLVVLE GCTVELAEAP VPEEFAFAIC FDAPGVRPHL LAAEGPAAQE AWVKVLSRAS FGYMRLVVRE LESQLQDARQ SLALQRRSSW KSVASRCKPQ APNHRAAGLE NGHCLSKDSS PVGLVEEAGS RSAGWGLAEW ELQGPASLLL GKGQSPVSPE TSCFSTLHDW YGQEIVELRQ CWQKRAQGSH SKCEEQDRP
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