About Retrotransposon Gag-like protein 6
Retrotransposon Gag-like protein 6 (RTL6) is a protein
from Homo sapiens identified by UniProt accession
Q6ICC9, 239 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Retrotransposon Gag-like protein 6 |
|---|
| UniProt accession | Q6ICC9 |
|---|
| Gene | RTL6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 239 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.30
- intelligence · score 0.30
- neurofibrillary tangles measurement · score 0.04
- Abnormality of the tongue · score 0.02
- neoplasm · score 0.00
- ovarian neoplasm · score 0.00
- ovarian carcinoma · score 0.00
- hepatitis C virus induced hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6ICC9-F1 | alphafold | PREDICTED | 77.31 | — |
Amino-acid sequence (239 residues)
MVQPQTSKAE SPALAASPNA QMDDVIDTLT SLRLTNSALR REASTLRAEK ANLTNMLESV MAELTLLRTR ARIPGALQIT PPISSITSNG TRPMTTPPTS LPEPFSGDPG RLAGFLMQMD RFMIFQASRF PGEAERVAFL VSRLTGEAEK WAIPHMQPDS PLRNNYQGFL AELRRTYKSP LRHARRAQIR KTSASNRAVR ERQMLCRQLA SAGTGPCPVH PASNGTSPAP ALPARARNL
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