Solute carrier family 35 member E4 (SLC35E4)

About Solute carrier family 35 member E4

Solute carrier family 35 member E4 (SLC35E4) is a protein from Homo sapiens identified by UniProt accession Q6ICL7, 350 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Solute carrier family 35 member E4
UniProt accession	Q6ICL7
Gene	SLC35E4
Organism	Homo sapiens
Length	350 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

body height · score 0.28
blood protein measurement · score 0.10
schizophrenia · score 0.08
Nephroblastoma · score 0.05
Red cell distribution width · score 0.04
mean reticulocyte volume · score 0.03
gonorrhea · score 0.01
psoriasis · score 0.01
chronic kidney disease · score 0.01
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6ICL7-F1	alphafold	PREDICTED	80.99	—

Amino-acid sequence (350 residues)

MCRCPPEHHD GRMTSAEVGA AAGGAQAAGP PEWPPGSPQA LRQPGRARVA MAALVWLLAG ASMSSLNKWI FTVHGFGRPL LLSALHMLVA ALACHRGARR PMPGGTRCRV LLLSLTFGTS MACGNVGLRA VPLDLAQLVT TTTPLFTLAL SALLLGRRHH PLQLAAMGPL CLGAACSLAG EFRTPPTGCG FLLAATCLRG LKSVQQSALL QEERLDAVTL LYATSLPSFC LLAGAALVLE AGVAPPPTAG DSRLWACILL SCLLSVLYNL ASFSLLALTS ALTVHVLGNL TVVGNLILSR LLFGSRLSAL SYVGIALTLS GMFLYHNCEF VASWAARRGL WRRDQPSKGL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards