About Olfactory receptor 4A47
Olfactory receptor 4A47 (OR4A47) is a protein
from Homo sapiens identified by UniProt accession
Q6IF82, 309 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Olfactory receptor 4A47 |
|---|
| UniProt accession | Q6IF82 |
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| Gene | OR4A47 |
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| Organism | Homo sapiens |
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| Length | 309 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- atrial fibrillation · score 0.41
- atrial flutter · score 0.41
- cardiac arrhythmia · score 0.40
- chronic obstructive pulmonary disease · score 0.32
- high density lipoprotein cholesterol measurement · score 0.29
- chronic lymphocytic leukemia · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- systolic blood pressure · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6IF82-F1 | alphafold | PREDICTED | 91.79 | — |
Amino-acid sequence (309 residues)
MEPRKNVTDF VLLGFTQNPK EQKVLFVMFL LFYILTMVGN LLIVVTVTVS ETLGSPMYFF LAGLSFIDII YSSSISPRLI SGLFFGNNSI SFQSCMAQLF IEHIFGGSEV FLLLVMAYDC YVAICKPLHY LVIMRQWVCV VLLVVSWVGG FLHSVFQLSI IYGLPFCGPN VIDHFFCDMY PLLKLVCTDT HAIGLLVVAN GGLACTIVFL LLLISYGVIL HSLKNLSQKG RQKALSTCSS HMTVVVFFFV PCIFMYARPA RTFPIDKSVS VFYTVITPML NPLIYTLRNS EMTSAMKKLW RRDLISSST
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