About Olfactory receptor 52E8
Olfactory receptor 52E8 (OR52E8) is a protein
from Homo sapiens identified by UniProt accession
Q6IFG1, 313 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Olfactory receptor 52E8 |
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| UniProt accession | Q6IFG1 |
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| Gene | OR52E8 |
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| Organism | Homo sapiens |
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| Length | 313 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (10)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- low grade glioma · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- acute myeloid leukemia · score 0.14
- myocardial infarction · score 0.08
- coronary artery disease · score 0.07
- platelet count · score 0.05
- mean platelet volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6IFG1-F1 | alphafold | PREDICTED | 88.38 | — |
Amino-acid sequence (313 residues)
MSTSNHTQFH PSSFLLLGIP GLEDVHIWIG VPFFFVYLVA LLGNTALLFV IQTEQSLHEP MYYFLAMLDS IDLGLSTATI PKMLGIFWFN TKEISFGGCL SHMFFIHFFT AMESIVLVAM AFDRYIAICK PLRYTMILTS KIISLIAGIA VLRSLYMVVP LVFLLLRLPF CGHRIIPHTY CEHMGIARLA CASIKVNIRF GLGNISLLLL DVILIILSYV RILYAVFCLP SWEARLKALN TCGSHIGVIL AFFTPAFFSF LTHRFGHNIP QYIHIILANL YVVVPPALNP VIYGVRTKQI RERVLRIFLK TNH
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