Olfactory receptor 6B2 (OR6B2)

Homo sapiens — UniProt Q6IFH4

Gene: OR6B2Homo sapiensSwissProt reviewed

About Olfactory receptor 6B2

Olfactory receptor 6B2 (OR6B2) is a protein from Homo sapiens identified by UniProt accession Q6IFH4, 312 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein nameOlfactory receptor 6B2
UniProt accessionQ6IFH4
GeneOR6B2
OrganismHomo sapiens
Length312 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • DNA methylation · score 0.22
  • sensory perception of smell · score 0.17
  • acute myeloid leukemia · score 0.15
  • brain aneurysm · score 0.02
  • neoplasm · score 0.01
  • anaplastic large cell lymphoma · score 0.00
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6IFH4-F1alphafoldPREDICTED85.00—

Amino-acid sequence (312 residues)

MSGENVTKVS TFILVGLPTA PGLQYLLFLL FLLTYLFVLV ENLAIILIVW SSTSLHRPMY YFLSSMSFLE IWYVSDITPK MLEGFLLQQK RISFVGCMTQ LYFFSSLVCT ECVLLASMAY DRYVAICHPL RYHVLVTPGL CLQLVGFSFV SGFTISMIKV CFISSVTFCG SNVLNHFFCD ISPILKLACT DFSTAELVDF ILAFIILVFP LLATILSYWH ITLAVLRIPS ATGCWRAFST CASHLTVVTV FYTALLFMYV RPQAIDSQSS NKLISAVYTV VTPIINPLIY CLRNKEFKDA LKKALGLGQT SH

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Quick facts

UniProtQ6IFH4
GeneOR6B2
OrganismHomo sapiens
Length312
Binders0
Diseases7
View on UniProt