Electron transfer flavoprotein regulatory factor 1…

About Electron transfer flavoprotein regulatory factor 1

Electron transfer flavoprotein regulatory factor 1 (ETFRF1) is a protein from Homo sapiens identified by UniProt accession Q6IPR1, 90 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Electron transfer flavoprotein regulatory factor 1
UniProt accession	Q6IPR1
Gene	ETFRF1
Organism	Homo sapiens
Length	90 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

Noonan syndrome · score 0.19
cardiofaciocutaneous syndrome · score 0.18
metabolite measurement · score 0.15
Noonan syndrome and Noonan-related syndrome · score 0.12
sphingomyelin measurement · score 0.10
heel bone mineral density · score 0.05
non-small cell lung carcinoma · score 0.04
Abnormal sperm morphology · score 0.03
ovarian carcinoma · score 0.01
rasopathy · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6IPR1-F1	alphafold	PREDICTED	91.06	—

Amino-acid sequence (90 residues)

MKMANSLRGE VLKLYKNLLY LGRDYPKGAD YFKKRLKNIF LKNKDVKNPE KIKELIAQGE FVMKELEALY FLRKYRAMKQ RYYSDTNKTN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Electron transfer flavoprotein regulatory factor 1 (ETFRF1)