Golgi-associated RAB2 interactor protein 5A (GARIN5A)

About Golgi-associated RAB2 interactor protein 5A

Golgi-associated RAB2 interactor protein 5A (GARIN5A) is a protein from Homo sapiens identified by UniProt accession Q6IPT2, 247 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Golgi-associated RAB2 interactor protein 5A
UniProt accession	Q6IPT2
Gene	GARIN5A
Organism	Homo sapiens
Length	247 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

neurodevelopmental disorder with dysmorphic facies and variable seizures · score 0.40
genetic disorder · score 0.15
red blood cell density measurement · score 0.14
hemoglobin measurement · score 0.12
hematocrit · score 0.12
atrial flutter · score 0.08
atrial fibrillation · score 0.08
cardiac arrhythmia · score 0.04
chronic obstructive pulmonary disease · score 0.04
pancreatic adenocarcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6IPT2-F1	alphafold	PREDICTED	64.61	—

Amino-acid sequence (247 residues)

MGPPLWPDLQ EPPPPGTSSQ IRSPLLCDVI KPAPHHDVTV RVVPPPRFLP LLLRPLPSDG DIAMRRDRGP KPALGGAGEV EPGGMAASPT GRPRRLQRYL QSGEFDQFRD FPIFESNFVQ FCPDIYPAPT SDLWPQVTRL GEVANEVTMG VAASSPALEL PDLLLLAGPA KENGHLQLFG LFPLKFVQLF VHDKSRCQLE VKLNTSRTFY LQLRAPLKTR DREFGQWVRL LYRLRFLSAS AVPFTQE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards