About NADH-cytochrome b5 reductase-like
NADH-cytochrome b5 reductase-like (CYB5RL) is a protein
from Homo sapiens identified by UniProt accession
Q6IPT4, 315 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | NADH-cytochrome b5 reductase-like |
|---|
| UniProt accession | Q6IPT4 |
|---|
| Gene | CYB5RL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 315 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- electrocardiography · score 0.18
- body mass index · score 0.14
- TPE interval measurement · score 0.14
- age at menarche · score 0.12
- P wave duration · score 0.12
- monocyte count · score 0.12
- PR interval · score 0.11
- lean body mass · score 0.10
- sodium measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6IPT4-F1 | alphafold | PREDICTED | 92.10 | — |
Amino-acid sequence (315 residues)
MMAEREEDDD TEEAWMQLRP TEPLPSQCCG SGCSPCVFDL YHRDLARWEA AQASKDRSLL RGPESQSCPS KLNPETFVAF CIIAMDRLTK DTYRVRFALP GNSQLGLRPG QHLILRGIVD DLEIQRAYTP ISPANAEGYF EVLIKCYQMG LMSRYVESWR VGDTAFWRGP FGDFFYKPNQ YGELLLLAAG TGLAPMVPIL QSITDNENDE TFVTLVGCFK TFESIYLKTF LQEQARFWNV RTFFVLSQES SSEQLPWSYQ EKTHFGHLGQ DLIKELVSCC RRKPFALVCG SAEFTKDIAR CLLCAGLTED SYFLF
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