About Polypeptide N-acetylgalactosaminyltransferase 17
Polypeptide N-acetylgalactosaminyltransferase 17 (GALNT17) is a protein
from Homo sapiens identified by UniProt accession
Q6IS24, 598 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 17 |
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| UniProt accession | Q6IS24 |
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| Gene | GALNT17 |
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| Organism | Homo sapiens |
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| Length | 598 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (50)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.29
- smoking behavior · score 0.28
- stomach neoplasm · score 0.21
- blood protein measurement · score 0.17
- protein measurement · score 0.14
- body height · score 0.09
- lymphocyte count · score 0.09
- appendicular lean mass · score 0.08
- mathematical ability · score 0.08
- lean body mass · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6IS24-F1 | alphafold | PREDICTED | 90.46 | — |
Amino-acid sequence (598 residues)
MASLRRVKVL LVLNLIAVAG FVLFLAKCRP IAVRSGDAFH EIRPRAEVAN LSAHSASPIQ DAVLKRLSLL EDIVYRQLNG LSKSLGLIEG YGGRGKGGLP ATLSPAEEEK AKGPHEKYGY NSYLSEKISL DRSIPDYRPT KCKELKYSKD LPQISIIFIF VNEALSVILR SVHSAVNHTP THLLKEIILV DDNSDEEELK VPLEEYVHKR YPGLVKVVRN QKREGLIRAR IEGWKVATGQ VTGFFDAHVE FTAGWAEPVL SRIQENRKRV ILPSIDNIKQ DNFEVQRYEN SAHGYSWELW CMYISPPKDW WDAGDPSLPI RTPAMIGCSF VVNRKFFGEI GLLDPGMDVY GGENIELGIK VWLCGGSMEV LPCSRVAHIE RKKKPYNSNI GFYTKRNALR VAEVWMDDYK SHVYIAWNLP LENPGIDIGD VSERRALRKS LKCKNFQWYL DHVYPEMRRY NNTVAYGELR NNKAKDVCLD QGPLENHTAI LYPCHGWGPQ LARYTKEGFL HLGALGTTTL LPDTRCLVDN SKSRLPQLLD CDKVKSSLYK RWNFIQNGAI MNKGTGRCLE VENRGLAGID LILRSCTGQR WTIKNSIK
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