About Mitochondrial adenyl nucleotide antiporter SLC25A25
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) is a protein
from Homo sapiens identified by UniProt accession
Q6KCM7, 469 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Mitochondrial adenyl nucleotide antiporter SLC25A25 |
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| UniProt accession | Q6KCM7 |
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| Gene | SLC25A25 |
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| Organism | Homo sapiens |
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| Length | 469 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (51)
Diseases linked to this target (Open Targets).
- nephrolithiasis · score 0.33
- pathological myopia · score 0.11
- Myopia · score 0.11
- non-small cell lung carcinoma · score 0.08
- pachyonychia congenita · score 0.07
- monocyte count · score 0.07
- urate measurement · score 0.04
- myeloid white cell count · score 0.03
- uric acid measurement · score 0.03
- neutrophil count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6KCM7-F1 | alphafold | PREDICTED | 73.95 | — |
Amino-acid sequence (469 residues)
MLCLCLYVPV IGEAQTEFQY FESKGLPAEL KSIFKLSVFI PSQEFSTYRQ WKQKIVQAGD KDLDGQLDFE EFVHYLQDHE KKLRLVFKSL DKKNDGRIDA QEIMQSLRDL GVKISEQQAE KILKSMDKNG TMTIDWNEWR DYHLLHPVEN IPEIILYWKH STIFDVGENL TVPDEFTVEE RQTGMWWRHL VAGGGAGAVS RTCTAPLDRL KVLMQVHASR SNNMGIVGGF TQMIREGGAR SLWRGNGINV LKIAPESAIK FMAYEQIKRL VGSDQETLRI HERLVAGSLA GAIAQSSIYP MEVLKTRMAL RKTGQYSGML DCARRILARE GVAAFYKGYV PNMLGIIPYA GIDLAVYETL KNAWLQHYAV NSADPGVFVL LACGTMSSTC GQLASYPLAL VRTRMQAQAS IEGAPEVTMS SLFKHILRTE GAFGLYRGLA PNFMKVIPAV SISYVVYENL KITLGVQSR
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