About Tigger transposable element-derived protein 7
Tigger transposable element-derived protein 7 (TIGD7) is a protein
from Homo sapiens identified by UniProt accession
Q6NT04, 549 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Tigger transposable element-derived protein 7 |
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| UniProt accession | Q6NT04 |
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| Gene | TIGD7 |
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| Organism | Homo sapiens |
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| Length | 549 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.13
- Cystic Kidney Disease · score 0.11
- Genetic renal or urinary tract malformation · score 0.11
- substance abuse · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- antisocial behaviour measurement · score 0.09
- BMI-adjusted waist-hip ratio · score 0.07
- serum gamma-glutamyl transferase measurement · score 0.07
- IGF-1 measurement · score 0.05
- serum alanine aminotransferase measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6NT04-F1 | alphafold | PREDICTED | 71.85 | — |
Amino-acid sequence (549 residues)
MNKRGKYTTL NLEEKMKVLS RIEAGRSLKS VMDEFGISKS TFYDIKKNKK LILDFVLKQD MPLVGAEKRK RTTGAKYGDV DDAVYMWYQQ KRSAGVPVRG VELQAAAERF ARCFGRTDFK ASTGWLFRFR NRHAIGNRKG CGEQVLSSVS ENVEPFRQKL SMIIKEEKLC LAQLYSGDET DLFWKSMPEN SQASRKDICL PGKKINKERL SAFLCANADG THKLKSIIIG KSKLPKSVKE DTSTLPVIYK PSKDVWFTRE LFSEWFFQNF VPEVRHFQLN VLRFHDEDVR ALLLLDSCPA HPSSESLTSE DGRIKCMFFP HNTSTLIQPM NQGVILSCKR LYRWKQLEES LVIFEESDDE QEKGDKGVSK IKIYNIKSAI FNWAKSWEEV KQITIANAWE NLLYKKEPEY DFQGLEHGDY REILEKCGEL ETKLDDDRVW LNGDEEKGCL LKTKGGITKE VVQKGGEAEK QTAEFKLSAV RESLDYLLDF VDATPEFQRF HFTLKEMQQE IVKKQFQSKI HSRIGSFLKP RPHNIKDSFS GPSTSGSNH
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