G antigen 2A (GAGE2A)

About G antigen 2A

G antigen 2A (GAGE2A) is a protein from Homo sapiens identified by UniProt accession Q6NT46, 116 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	G antigen 2A
UniProt accession	Q6NT46
Gene	GAGE2A
Organism	Homo sapiens
Length	116 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

ovarian neoplasm · score 0.01
cancer · score 0.01
hepatocellular carcinoma · score 0.01
melanoma · score 0.01
neoplasm · score 0.00
prostate adenocarcinoma · score 0.00
non-small cell lung carcinoma · score 0.00
sarcoma · score 0.00
small cell lung carcinoma · score 0.00
multiple myeloma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6NT46-F1	alphafold	PREDICTED	65.68	—

Amino-acid sequence (116 residues)

MSWRGRSTYR PRPRRYVEPP EMIGPMRPEQ FSDEVEPATP EEGEPATQRQ DPAAAQEGQD EGASAGQGPK PEAHSQEQGH PQTGCECEDG PDGQEMDPPN PEEVKTPEEG EKQSQC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards