About Choriogonadotropin subunit beta variant 2
Choriogonadotropin subunit beta variant 2 (CGB2) is a protein
from Homo sapiens identified by UniProt accession
Q6NT52, 163 residues long.
MolForge cross-references it against 0 known binders and
276 disease associations.
Target properties
| Protein name | Choriogonadotropin subunit beta variant 2 |
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| UniProt accession | Q6NT52 |
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| Gene | CGB2 |
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| Organism | Homo sapiens |
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| Length | 163 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (276)
Diseases linked to this target (Open Targets).
- Kallmann syndrome · score 0.07
- isolated congenital hypogonadotropic hypogonadism · score 0.07
- 46,XX gonadal dysgenesis · score 0.07
- azoospermia · score 0.07
- hypogonadotropic hypogonadism · score 0.07
- primary ovarian insufficiency · score 0.07
- Testicular regression syndrome · score 0.06
- 46,XX testicular disorder of sex development · score 0.06
- partial androgen insensitivity syndrome · score 0.06
- Isolated follicle stimulating hormone deficiency · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6NT52-F1 | alphafold | PREDICTED | 77.89 | — |
Amino-acid sequence (163 residues)
MSKGLLLLLL LSMGGTWASK EPLRPRCRPI NATLAVEKEG CPVCITVNTT ICAGYCPTMT RVLQGVLPAL PQVVCNYRDV RFESIRLPGC PRGVNPVVSY AVALSCQCAL CRRSTTDCGG PKDHPLTCDD PRFQASSSSK APPPSLPSPS RLPGPSDTPI LPQ
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