Fanconi anemia core complex-associated protein 20…

About Fanconi anemia core complex-associated protein 20

Fanconi anemia core complex-associated protein 20 (FAAP20) is a protein from Homo sapiens identified by UniProt accession Q6NZ36, 180 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.

Target properties

Protein name	Fanconi anemia core complex-associated protein 20
UniProt accession	Q6NZ36
Gene	FAAP20
Organism	Homo sapiens
Length	180 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (77)

Diseases linked to this target (Open Targets).

urate measurement · score 0.35
electrocardiography · score 0.34
body height · score 0.31
platelet count · score 0.30
IGF-1 measurement · score 0.29
HbA1c measurement · score 0.28
PR interval · score 0.26
TPE interval measurement · score 0.21
uric acid measurement · score 0.20
breast adenocarcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6NZ36-F1	alphafold	PREDICTED	65.67	—

Amino-acid sequence (180 residues)

MEAARRPRLG LSRRRPRPAG GPSGGRPWFL LGGDERERLW AELLRTVSPE LILDHEVPSL PAFPGQEPRC GPEPTEVFTV GPKTFSWTPF PPDLWGPGRS YRLLHGAGGH LESPARSLPQ RPAPDPCRAP RVEQQPSVEG AAALRSCPMC QKEFAPRLTQ LDVDSHLAQC LAESTEDVTW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Fanconi anemia core complex-associated protein 20 (FAAP20)