Mitotic-spindle organizing protein 2B (MZT2B)

About Mitotic-spindle organizing protein 2B

Mitotic-spindle organizing protein 2B (MZT2B) is a protein from Homo sapiens identified by UniProt accession Q6NZ67, 158 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Mitotic-spindle organizing protein 2B
UniProt accession	Q6NZ67
Gene	MZT2B
Organism	Homo sapiens
Length	158 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
neoplasm · score 0.02
Alzheimer disease · score 0.00
gonorrhea · score 0.00
colorectal cancer · score 0.00
relapsing-remitting multiple sclerosis · score 0.00
Helicobacter pylori infectious disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6NZ67-F1	alphafold	PREDICTED	63.57	—

Amino-acid sequence (158 residues)

MAAQGVGPGP GSAAPPGLEA ARQKLALRRK KVLSTEEMEL YELAQAAGGA IDPDVFKILV DLLKLNVAPL AVFQMLKSMC AGQRLASEPQ DPAAVSLPTS SVPETRGRNK GSAALGGALA LAERSSREGS SQRMPRQPSA TRLPKGGGPG KSPTRGST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards