Arylacetamide deacetylase-like 2 (AADACL2)

About Arylacetamide deacetylase-like 2

Arylacetamide deacetylase-like 2 (AADACL2) is a protein from Homo sapiens identified by UniProt accession Q6P093, 401 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Arylacetamide deacetylase-like 2
UniProt accession	Q6P093
Gene	AADACL2
Organism	Homo sapiens
Length	401 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

neurofibrillary tangles measurement · score 0.27
ovarian carcinoma · score 0.03
hair shape measurement · score 0.03
androgenetic alopecia · score 0.02
vital capacity · score 0.02
alopecia · score 0.02
breast carcinoma · score 0.02
periodontitis · score 0.02
dysplasia · score 0.01
colorectal cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6P093-F1	alphafold	PREDICTED	95.36	—

Amino-acid sequence (401 residues)

MGLKALCLGL LCVLFVSHFY TPMPDNIEES WKIMALDAIA KTCTFTAMCF ENMRIMRYEE FISMIFRLDY TQPLSDEYIT VTDTTFVDIP VRLYLPKRKS ETRRRAVIYF HGGGFCFGSS KQRAFDFLNR WTANTLDAVV VGVDYRLAPQ HHFPAQFEDG LAAVKFFLLE KILTKYGVDP TRICIAGDSS GGNLATAVTQ QVQNDAEIKH KIKMQVLLYP GLQITDSYLP SHRENEHGIV LTRDVAIKLV SLYFTKDEAL PWAMRRNQHM PLESRHLFKF VNWSILLPEK YRKDYVYTEP ILGGLSYSLP GLTDSRALPL LANDSQLQNL PLTYILTCQH DLLRDDGLMY VTRLRNVGVQ VVHEHIEDGI HGALSFMTSP FYLRLGLRIR DMYVSWLDKN L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards