About WD repeat-containing protein 93
WD repeat-containing protein 93 (WDR93) is a protein
from Homo sapiens identified by UniProt accession
Q6P2C0, 686 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | WD repeat-containing protein 93 |
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| UniProt accession | Q6P2C0 |
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| Gene | WDR93 |
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| Organism | Homo sapiens |
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| Length | 686 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.20
- body height · score 0.05
- aspartate aminotransferase measurement · score 0.04
- serum alanine aminotransferase measurement · score 0.04
- ulcerative colitis · score 0.02
- neoplasm · score 0.01
- hepatocellular carcinoma · score 0.01
- nervous system disease · score 0.01
- squamous cell carcinoma · score 0.01
- influenza · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6P2C0-F1 | alphafold | PREDICTED | 77.54 | — |
Amino-acid sequence (686 residues)
MSFPRGSQTQ KIKHPIGTRK GPLEVPPPTE KDWPKDDEQD HVLVDPDEEL DSLPQPYRMI NKLVNLLFDQ SWEIIEERNA LREAESSQIQ PTVYPPLGEI QLNKMPNCMA VSQDYVFIGG AKGFSIYNLY SAKQIYAWEK LKVDVTSIWA TDLGNEILIA PVDEMGIIRL FYFYKEGLYL VKAINEVDDT SKQTTCIKME ISQGGDFAAF LLQGAGDIWL DVYKLPKETW LKKLEHPQLT SNPKKKVRQP QLNSLGPISA DPLEMDANVS FKGDIKLSLP VYIMKIKPPK PVTGTTFKSP LEVFAKIKDC YGLGSGQNHF IKDSQWEQQA EIFNASYKKY LDREWEEEPL STATFYFLLP SCLFAMPPEV KGPSGMACVL GIHWTRSHNF FLYSLNRTLK DKADPEGVWP CAAPIAVSQL SCSSSYLVLA CEDGVLTLWD LAKGFPLGVA ALPQGCFCQS IHFLKYFSVH KGQNMYPEGQ VKSQMKCVVL CTDASLHLVE ASGTQGPTIS VLVERPVKHL DKTICAVAPV PALPGMVLIF SKNGSVCLMD VAKREIICAF APPGAFPLEV PWKPVFAVSP DHPCFLLRGD YSHETASTDD AGIQYSVFYF NFEACPLLEN ISKNCTIPQR DLDNMAFPQA LPLEKRCERF LQKSYRKLEK NPEKEEEHWA RLQRYSLSLQ RENFKK
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