Zinc finger protein 1 homolog (ZFP1)

About Zinc finger protein 1 homolog

Zinc finger protein 1 homolog (ZFP1) is a protein from Homo sapiens identified by UniProt accession Q6P2D0, 407 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Zinc finger protein 1 homolog
UniProt accession	Q6P2D0
Gene	ZFP1
Organism	Homo sapiens
Length	407 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.39
body height · score 0.35
BMI-adjusted waist circumference · score 0.29
vital capacity · score 0.26
high density lipoprotein cholesterol measurement · score 0.26
eosinophil percentage of leukocytes · score 0.24
forced expiratory volume · score 0.21
sitting height measurement · score 0.12
eosinophil percentage of granulocytes · score 0.08
laryngeal squamous cell carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6P2D0-F1	alphafold	PREDICTED	65.58	—

Amino-acid sequence (407 residues)

MNKSQGSVSF TDVTVDFTQE EWEQLDPSQR ILYMDVMLEN YSNLLSVEVW KADDQMERDH RNPDEQARQF LILKNQTPIE ERGDLFGKAL NLNTDFVSLR QVPYKYDLYE KTLKYNSDLL NSNRSYAGKQ TDECNEFGKA LLYLKQEKTH SGVEYSEYNK SGKALSHKAA IFKHQKIKNL VQPFICTYCD KAFSFKSLLI SHKRIHTGEK PYECNVCKKT FSHKANLIKH QRIHTGEKPF ECPECGKAFT HQSNLIVHQR AHMEKKPYEC SECGKTFAQK FELTTHQRIH TGERPYECNE CAKTFFKKSN LIIHQKIHTG EKRYECSECG KSFIQNSQLI IHMRTHTGEK PYECTECGKT FSQRSTLRLH LRIHTGEKPY ECSECGKAFS RKSRLSVHQR VHIGEKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards