About Zinc finger protein 585A
Zinc finger protein 585A (ZNF585A) is a protein
from Homo sapiens identified by UniProt accession
Q6P3V2, 769 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Zinc finger protein 585A |
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| UniProt accession | Q6P3V2 |
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| Gene | ZNF585A |
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| Organism | Homo sapiens |
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| Length | 769 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (24)
Diseases linked to this target (Open Targets).
- body height · score 0.39
- forced expiratory volume · score 0.25
- appendicular lean mass · score 0.16
- eosinophil count · score 0.16
- glomerular filtration rate · score 0.13
- insomnia · score 0.11
- eosinophil percentage of leukocytes · score 0.10
- sitting height measurement · score 0.07
- BMI-adjusted waist circumference · score 0.07
- BMI-adjusted hip circumference · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6P3V2-F1 | alphafold | PREDICTED | 76.19 | — |
Amino-acid sequence (769 residues)
MPANWTSPQK SSALAPEDHG SSYEGSVSFR DVAIDFSREE WRHLDPSQRN LYRDVMLETY SHLLSVGYQV PEAEVVMLEQ GKEPWALQGE RPRQSCPGEK LWDHNQCRKI LSYKQVSSQP QKMYPGEKAY ECAKFEKIFT QKSQLKVHLK VLAGEKLYVC IECGKAFVQK PEFIIHQKTH MREKPFKCNE CGKSFFQVSS LFRHQRIHTG EKLYECSQCG KGFSYNSDLS IHEKIHTGER HHECTDCGKA FTQKSTLKMH QKIHTGERSY ICIECGQAFI QKTHLIAHRR IHTGEKPYEC SNCGKSFISK SQLQVHQRVH TRVKPYICTE YGKVFSNNSN LVTHKKVQSR EKSSICTECG KAFTYRSELI IHQRIHTGEK PYECSDCGKA FTQKSALTVH QRIHTGEKSY ICMKCGLAFI QKAHLIAHQI IHTGEKPHKC GHCGKLFTSK SQLHVHKRIH TGEKPYMCNK CGKAFTNRSN LITHQKTHTG EKSYICSKCG KAFTQRSDLI THQRIHTGEK PYECNTCGKA FTQKSHLNIH QKIHTGERQY ECHECGKAFN QKSILIVHQK IHTGEKPYVC TECGRAFIRK SNFITHQRIH TGEKPYECSD CGKSFTSKSQ LLVHQPVHTG EKPYVCAECG KAFSGRSNLS KHQKTHTGEK PYICSECGKT FRQKSELITH HRIHTGEKPY ECSDCGKSFT KKSQLQVHQR IHTGEKPYVC AECGKAFTDR SNLNKHQTTH TGDKPYKCGI CGKGFVQKSV FSVHQSSHA
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