DnaJ homolog subfamily C member 24 (DNAJC24)

About DnaJ homolog subfamily C member 24

DnaJ homolog subfamily C member 24 (DNAJC24) is a protein from Homo sapiens identified by UniProt accession Q6P3W2, 149 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	DnaJ homolog subfamily C member 24
UniProt accession	Q6P3W2
Gene	DNAJC24
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (83)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
aniridia · score 0.33
isolated aniridia · score 0.33
glomerular filtration rate · score 0.31
refractive error measurement · score 0.18
hemoglobin measurement · score 0.16
Hip pain · score 0.12
body mass index · score 0.11
sodium measurement · score 0.11
cortical surface area measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6P3W2-F1	alphafold	PREDICTED	74.54	—

Amino-acid sequence (149 residues)

MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG TVEECVQKFI EIDQAWKILG NEETKREYDL QRCEDDLRNV GPVDAQVYLE EMSWNEGDHS FYLSCRCGGK YSVSKDEAEE VSLISCDTCS LIIELLHYN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards