About Oxaloacetate tautomerase FAHD1, mitochondrial
Oxaloacetate tautomerase FAHD1, mitochondrial (FAHD1) is a protein
from Homo sapiens identified by UniProt accession
Q6P587, 221 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Oxaloacetate tautomerase FAHD1, mitochondrial |
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| UniProt accession | Q6P587 |
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| Gene | FAHD1 |
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| Organism | Homo sapiens |
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| Length | 221 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- spermatogenic failure 22 · score 0.33
- azoospermia · score 0.33
- mean corpuscular hemoglobin · score 0.10
- platelet crit · score 0.07
- mean corpuscular volume · score 0.07
- body height · score 0.06
- insulin like growth factor measurement · score 0.05
- calcium measurement · score 0.05
- sex hormone-binding globulin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6P587-F1 | alphafold | PREDICTED | 95.97 | — |
Amino-acid sequence (221 residues)
MAASRPLSRF WEWGKNIVCV GRNYADHVRE MRSAVLSEPV LFLKPSTAYA PEGSPILMPA YTRNLHHELE LGVVMGKRCR AVPEAAAMDY VGGYALCLDM TARDVQDECK KKGLPWTLAK SFTASCPVSA FVPKEKIPDP HKLKLWLKVN GELRQEGETS SMIFSIPYII SYVSKIITLE EGDIILTGTP KGVGPVKEND EIEAGIHGLV SMTFKVEKPE Y
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