Cilia- and flagella-associated protein 161 (CFAP161)

Homo sapiens — UniProt Q6P656

Gene: CFAP161Homo sapiensSwissProt reviewed

About Cilia- and flagella-associated protein 161

Cilia- and flagella-associated protein 161 (CFAP161) is a protein from Homo sapiens identified by UniProt accession Q6P656, 301 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein nameCilia- and flagella-associated protein 161
UniProt accessionQ6P656
GeneCFAP161
OrganismHomo sapiens
Length301 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6P656-F1alphafoldPREDICTED87.06—

Amino-acid sequence (301 residues)

MAQNVYGPGV RIGNWNEDVY LEEELMKDFL EKRDKGKLLI QRSRRLKQNL LRPMQLSVTE DGYIHYGDKV MLVNPDDPDT EADVFLRGDL SLCMTPDEIQ SHLKDELEVP CGLSAVQAKT PIGRNTFIIL SVHRDATGQV LRYGQDFCLG ITGGFDNKML YLSSDHRTLL KSSKRSWLQE VYLTDEVSHV NCWQAAFPDP QLRLEYEGFP VPANAKILIN HCHTNRGLAA HRHLFLSTYF GKEAEVVAHT YLDSHRVEKP RNHWMLVTGN PRDASSSMLD LPKPPTEDTR AMEQAMGLDT Q

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Quick facts

UniProtQ6P656
GeneCFAP161
OrganismHomo sapiens
Length301
Binders0
Diseases26
View on UniProt