About Protein FAM171B
Protein FAM171B (FAM171B) is a protein
from Homo sapiens identified by UniProt accession
Q6P995, 826 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Protein FAM171B |
|---|
| UniProt accession | Q6P995 |
|---|
| Gene | FAM171B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 826 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- body height · score 0.40
- blood protein measurement · score 0.39
- brain volume measurement · score 0.29
- neuroimaging measurement · score 0.29
- FEV/FVC ratio · score 0.24
- vital capacity · score 0.21
- blood phosphate measurement · score 0.20
- inflammatory bowel disease · score 0.20
- asthma · score 0.18
- handedness · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6P995-F1 | alphafold | PREDICTED | 56.88 | — |
Amino-acid sequence (826 residues)
MARLCRRVPC TLLLGLAVVL LKARLVPAAA RAELSRSDLS LIQQQQQQQQ QQQQQQKQLE EAEEERTEVP GATSTLTVPV SVFMLKVQVN DIISRQYLSQ AVVEVFVNYT KTNSTVTKSN GAVLIKVPYK LGLSLTIIAY KDGYVLTPLP WKTRRMPIYS SVTLSLFPQS QANIWLFEDT VLITGKLADA KSQPSVQFSK ALIKLPDNHH ISNVTGYLTV LQQFLKVDNF LHTTGITLNK PGFENIELTP LAAICVKIYS GGKELKVNGS IQVSLPLLRL NDISAGDRIP AWTFDMNTGA WVNHGRGMVK EHNNHLIWTY DAPHLGYWIA APLPGTRGSG INEDSKDITA YHTVFLTAIL GGTIVIVIGF FAVLLCYCRD KCGTPQKRER NITKLEVLKR DQTTSTTHIN HISTVKVALK AEDKSQLFNA KNSSYSPQKK EPSKAETEER VSMVKTRDDF KIYNEDVSFL SVNQNNYSRN PTQSLEPNVG SKQPKHINNN LSSSLGDAQD EKRYLTGNEE AYGRSHIPEQ LMHIYSQPIA ILQTSDLFST PEQLHTAKSA TLPRKGQLVY GQLMEPVNRE NFTQTLPKMP IHSHAQPPDA REEDIILEGQ QSLPSQASDW SRYSSSLLES VSVPGTLNEA VVMTPFSSEL QGISEQTLLE LSKGKPSPHP RAWFVSLDGK PVAQVRHSFI DLKKGKRTQS NDTSLDSGVD MNELHSSRKL EREKTFIKSM HQPKILYLED LDLSSSESGT TVCSPEDPAL RHILDGGSGV IMEHPGEESP GRKSTVEDFE ANTSPTKRRG RPPLAKRDSK TNIWKKREER PLIPIN
Explore Protein FAM171B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets