MTOR-associated protein MEAK7 (MEAK7)

About MTOR-associated protein MEAK7

MTOR-associated protein MEAK7 (MEAK7) is a protein from Homo sapiens identified by UniProt accession Q6P9B6, 456 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	MTOR-associated protein MEAK7
UniProt accession	Q6P9B6
Gene	MEAK7
Organism	Homo sapiens
Length	456 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.49
monocyte count · score 0.48
leukocyte count · score 0.47
mean platelet volume · score 0.45
myeloid white cell count · score 0.43
neutrophil count · score 0.43
basophil count · score 0.41
mean corpuscular hemoglobin concentration · score 0.40
HbA1c measurement · score 0.36
platelet crit · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6P9B6-F1	alphafold	PREDICTED	86.33	—

Amino-acid sequence (456 residues)

MGNSRSRVGR SFCSQFLPEE QAEIDQLFDA LSSDKNSPNV SSKSFSLKAL QNHVGEALPP EMVTRLYDGM RRVDLTGKAK GPSENVSQEQ FTASMSHLLK GNSEEKSLMI MKMISATEGP VKAREVQKFT EDLVGSVVHV LSHRQELRGW TGKEAPGPNP RVQVLAAQLL SDMKLQDGKR LLGPQWLDYD CDRAVIEDWV FRVPHVAIFL SVVICKGFLI LCSSLDLTTL VPERQVDQGR GFESILDVLS VMYINAQLPR EQRHRWCLLF SSELHGHSFS QLCGHITHRG PCVAVLEDHD KHVFGGFASC SWEVKPQFQG DNRCFLFSIC PSMAVYTHTG YNDHYMYLNH GQQTIPNGLG MGGQHNYFGL WVDVDFGKGH SRAKPTCTTY NSPQLSAQEN FQFDKMEVWA VGDPSEEQLA KGNKSILDAD PEAQALLEIS GHSRHSEGLR EVPDDE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards