About Coiled-coil domain-containing protein 62
Coiled-coil domain-containing protein 62 (CCDC62) is a protein
from Homo sapiens identified by UniProt accession
Q6P9F0, 684 residues long.
MolForge cross-references it against 0 known binders and
123 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 62 |
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| UniProt accession | Q6P9F0 |
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| Gene | CCDC62 |
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| Organism | Homo sapiens |
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| Length | 684 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (123)
Diseases linked to this target (Open Targets).
- spermatogenic failure 67 · score 0.47
- Parkinson disease · score 0.29
- high density lipoprotein cholesterol measurement · score 0.23
- HbA1c measurement · score 0.13
- apolipoprotein A 1 measurement · score 0.13
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.11
- schizophrenia · score 0.09
- spermatogenic failure 72 · score 0.09
- spermatogenic failure 46 · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6P9F0-F1 | alphafold | PREDICTED | 64.36 | — |
Amino-acid sequence (684 residues)
MNPPAAFLAG RQNIGSEVEI STIEKQRKEL QLLIGELKDR DKELNDMVAV HQQQLLSWEE DRQKVLTLEE RCSKLEGELH KRTEIIRSLT KKVKALESNQ MECQTALQKT QLQLQEMAQK ATHSSLLSED LEARNETLSN TLVELSAQVG QLQAREQALT TMIKLKDKDI IEAVNHIADC SGKFKMLEHA LRDAKMAETC IVKEKQDYKQ KLKALKIEVN KLKEDLNEKT TENNEQREEI IRLKQEKSCL HDELLFTVER EKRKDELLNI AKSKQERTNS ELHNLRQIYV KQQSDLQFLN FNVENSQELI QMYDSKMEES KALDSSRDMC LSDLENNHPK VDIKREKNQK SLFKDQKFEA MLVQQNRSDK SSCDECKEKK QQIDTVFGEK SVITLSSIFT KDLVEKHNLP WSLGGKTQIE PENKITLCKI HTKSPKCHGT GVQNEGKQPS ETPTLSDEKQ WHDVSVYLGL TNCPSSKHPE KLDVECQDQM ERSEISCCQK NEACLGESGM CDSKCCHPSN FIIEAPGHMS DVEWMSIFKP SKMQRIVRLK SGCTCSESIC GTQHDSPASE LIAIQDSHSL GSSKSALRED ETESSSNKKN SPTSLLIYKD APAFNEKASI VLPSQDDFSP TSKLQRLLAE SRQMVTDLEL STLLPISHEN LTGSATNKSE VPEESAQKNT FVSY
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