About Long-chain fatty acid transport protein 1
Long-chain fatty acid transport protein 1 (SLC27A1) is a protein
from Homo sapiens identified by UniProt accession
Q6PCB7, 646 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Long-chain fatty acid transport protein 1 |
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| UniProt accession | Q6PCB7 |
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| Gene | SLC27A1 |
|---|
| Organism | Homo sapiens |
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| Length | 646 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.15
- neoplasm · score 0.08
- breast cancer · score 0.08
- triple-negative breast cancer · score 0.06
- Pituitary Gland Adenoma · score 0.04
- glioblastoma · score 0.03
- Insulin resistance · score 0.03
- cancer · score 0.02
- gestational diabetes · score 0.02
- insulin resistance · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PCB7-F1 | alphafold | PREDICTED | 90.91 | — |
Amino-acid sequence (646 residues)
MRAPGAGAAS VVSLALLWLL GLPWTWSAAA ALGVYVGSGG WRFLRIVCKT ARRDLFGLSV LIRVRLELRR HQRAGHTIPR IFQAVVQRQP ERLALVDAGT GECWTFAQLD AYSNAVANLF RQLGFAPGDV VAIFLEGRPE FVGLWLGLAK AGMEAALLNV NLRREPLAFC LGTSGAKALI FGGEMVAAVA EVSGHLGKSL IKFCSGDLGP EGILPDTHLL DPLLKEASTA PLAQIPSKGM DDRLFYIYTS GTTGLPKAAI VVHSRYYRMA AFGHHAYRMQ AADVLYDCLP LYHSAGNIIG VGQCLIYGLT VVLRKKFSAS RFWDDCIKYN CTVVQYIGEI CRYLLKQPVR EAERRHRVRL AVGNGLRPAI WEEFTERFGV RQIGEFYGAT ECNCSIANMD GKVGSCGFNS RILPHVYPIR LVKVNEDTME LLRDAQGLCI PCQAGEPGLL VGQINQQDPL RRFDGYVSES ATSKKIAHSV FSKGDSAYLS GDVLVMDELG YMYFRDRSGD TFRWRGENVS TTEVEGVLSR LLGQTDVAVY GVAVPGVEGK AGMAAVADPH SLLDPNAIYQ ELQKVLAPYA RPIFLRLLPQ VDTTGTFKIQ KTRLQREGFD PRQTSDRLFF LDLKQGHYLP LNEAVYTRIC SGAFAL
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