About Embigin
Embigin (EMB) is a protein
from Homo sapiens identified by UniProt accession
Q6PCB8, 327 residues long.
MolForge cross-references it against 0 known binders and
111 disease associations.
Target properties
| Protein name | Embigin |
|---|
| UniProt accession | Q6PCB8 |
|---|
| Gene | EMB |
|---|
| Organism | Homo sapiens |
|---|
| Length | 327 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (111)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.35
- leukocyte count · score 0.35
- neutrophil count · score 0.35
- type 2 diabetes mellitus · score 0.34
- age at first sexual intercourse measurement · score 0.32
- hair colour measurement · score 0.28
- electrocardiography · score 0.28
- myeloid white cell count · score 0.27
- FEV/FVC ratio · score 0.27
- Abnormality of refraction · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PCB8-F1 | alphafold | PREDICTED | 77.53 | — |
Amino-acid sequence (327 residues)
MRALPGLLEA RARTPRLLLL QCLLAAARPS SADGSAPDSP FTSPPLREEI MANNFSLESH NISLTEHSSM PVEKNITLER PSNVNLTCQF TTSGDLNAVN VTWKKDGEQL ENNYLVSATG STLYTQYRFT IINSKQMGSY SCFFREEKEQ RGTFNFKVPE LHGKNKPLIS YVGDSTVLTC KCQNCFPLNW TWYSSNGSVK VPVGVQMNKY VINGTYANET KLKITQLLEE DGESYWCRAL FQLGESEEHI ELVVLSYLVP LKPFLVIVAE VILLVATILL CEKYTQKKKK HSDEGKEFEQ IEQLKSDDSN GIENNVPRHR KNESLGQ
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