Zinc finger protein 880 (ZNF880)

About Zinc finger protein 880

Zinc finger protein 880 (ZNF880) is a protein from Homo sapiens identified by UniProt accession Q6PDB4, 577 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 880
UniProt accession	Q6PDB4
Gene	ZNF880
Organism	Homo sapiens
Length	577 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

colorectal carcinoma · score 0.08
neoplasm · score 0.05
cancer · score 0.05
reading · score 0.02
Acute hepatic failure · score 0.01
atrial fibrillation · score 0.01
Adams-Oliver syndrome · score 0.00
head and neck squamous cell carcinoma · score 0.00
acute lymphoblastic leukemia · score 0.00
endometrial carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PDB4-F1	alphafold	PREDICTED	69.34	—

Amino-acid sequence (577 residues)

MLRRGHLAFR DVAIEFPQEE WKCLDPAQRT LYREVMVENY RNLVFLGICL PDLSVISMLE QRRDPRNLQS EVKIANNPGG RECIKGVNAE SSSKLGSNAG NKSLKNQLGL TFQLHLSELQ LFQAERNISG CKHVEKPINN SLVSPLQKIY SSVKSHILNK YRNDFDDSPF LPQEQKAQIR EKPCECNEHG KAFRVSSRLA NNQVIHTADN PYKCNECDKV FSNSSNLVQH QRIHTGEKPY KCHECGKLFN RISLLARHQR IHTGEKPYKC HECGKVFTQN SHLANHHRIH TGEKPYKCNE CGKVFNRNAH LARHQKIHSG EKPYKCKECG KAFSGGSGLT AHLVIHTGEK LYKCNKCGKV FNRNAHLTRH QRIHTGEKPY ECKECGKVFR HKFCLTNHHR MHTGEQPYKC NECGKAFRDC SGLTAHLLIH TGEKPYKCKE CAKVFRHRLS LSNHQRFHTG EKPYRCDECG KDFTRNSNLA NHHRIHTGEK PYKCSECHKV FSHNSHLARH RQIHTGEKSY KCNECGKVFS HKLYLKKHER IHTGEKPYRC HECGKDFTRN SNLANHHRIH TGEKPYR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards