About Testis-expressed protein 38
Testis-expressed protein 38 (TEX38) is a protein
from Homo sapiens identified by UniProt accession
Q6PEX7, 206 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Testis-expressed protein 38 |
|---|
| UniProt accession | Q6PEX7 |
|---|
| Gene | TEX38 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.06
- osteomesopyknosis · score 0.06
- Kallmann syndrome · score 0.05
- male infertility with teratozoospermia due to single gene mutation · score 0.04
- primary ovarian insufficiency · score 0.04
- familial hyperprolactinemia · score 0.04
- osteosclerosis-ichthyosis-premature ovarian failure syndrome · score 0.04
- melorheostosis · score 0.04
- spermatogenic failure 61 · score 0.04
- osteoporosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PEX7-F1 | alphafold | PREDICTED | 59.82 | — |
Amino-acid sequence (206 residues)
MDSQQEDLRF PGMWVSLYFG ILGLCSVITG GCIIFLHWRK NLRREEHAQQ WVEVMRAATF TYSPLLYWIN KRRRYGMNAA INTGPAPAVT KTETEVQNPD VLWDLDIPEG RSHADQDSNP KAEAPAPLQP ALQLAPQQPQ ARSPFPLPIF QEVPFAPPLC NLPPLLNHSV SYPLATCPER NVLFHSLLNL AQEDHSFNAK PFPSEL
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