Tubulin alpha-3E chain (TUBA3E)

About Tubulin alpha-3E chain

Tubulin alpha-3E chain (TUBA3E) is a protein from Homo sapiens identified by UniProt accession Q6PEY2, 450 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein name	Tubulin alpha-3E chain
UniProt accession	Q6PEY2
Gene	TUBA3E
Organism	Homo sapiens
Length	450 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (103)

Diseases linked to this target (Open Targets).

viral disease · score 0.46
urinary bladder cancer · score 0.38
lung cancer · score 0.37
malignant epithelial tumor of ovary · score 0.37
fallopian tube neoplasm · score 0.37
peritoneal neoplasm · score 0.37
breast cancer · score 0.37
non-small cell lung carcinoma · score 0.37
neoplasm · score 0.35
neutropenia · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PEY2-F1	alphafold	PREDICTED	91.14	—

Amino-acid sequence (450 residues)

MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA SNYARGHYTI GKEIVDLVLD RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YSKKSKLEFA IYPAPQVSTA VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LVHKFDLMYA KWAFVHWYVG EGMEEGEFSE AREDLAALEK DCEEVGVDSV EAEAEEGEAY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards