Tetratricopeptide repeat protein 23-like (TTC23L)

About Tetratricopeptide repeat protein 23-like

Tetratricopeptide repeat protein 23-like (TTC23L) is a protein from Homo sapiens identified by UniProt accession Q6PF05, 361 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Tetratricopeptide repeat protein 23-like
UniProt accession	Q6PF05
Gene	TTC23L
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

drug use measurement · score 0.15
hair colour measurement · score 0.05
erythrocyte count · score 0.03
cystatin C measurement · score 0.02
creatinine measurement · score 0.02
serum urea measurement · score 0.02
beta-aminoisobutyric acid measurement · score 0.02
mastitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PF05-F1	alphafold	PREDICTED	84.14	—

Amino-acid sequence (361 residues)

MQASPIRIPT VSNDIDWDFC FHMSQQTEIP AHQQTDELYP TGGCGESEEE TKAKEKEKAI DCMSHPKEKL AQSQKKVAQL IKEKMNTQAN KELIRCVILS RIIFGDHHWK CARALANLAY GYLTLRGLPV QAKKHATSAK NTLLTWKANT TSNKEKEEIL EALVKLYYTL GVAWLLQNRG REAYFNLQKA ERNMKELKEL YKGGVCELQV SENDLTLALG RASLAIHRLN LALAYFEKAI GDVIAAKGDR TSDLISLYEE AAQIEQLRRN HNQAIQYLQQ AHSVCVSLFT EVSPKTAEMS ALLAKAYAMS GEAQHRDAVE IYFIRSINAY RATLGSEDFE TLSTTEEFCK WLVQNGEKQD K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards