MORN repeat-containing protein 3 (MORN3)

About MORN repeat-containing protein 3

MORN repeat-containing protein 3 (MORN3) is a protein from Homo sapiens identified by UniProt accession Q6PF18, 240 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	MORN repeat-containing protein 3
UniProt accession	Q6PF18
Gene	MORN3
Organism	Homo sapiens
Length	240 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.28
body fat percentage · score 0.19
lymphocyte count · score 0.08
fat body mass · score 0.07
primary familial polycythemia due to EPO receptor mutation · score 0.07
Pyruvate kinase hyperactivity · score 0.07
reticulocyte count · score 0.07
alpha thalassemia-intellectual disability syndrome type 1 · score 0.06
Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.06
erythrocytosis, familial, 6 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PF18-F1	alphafold	PREDICTED	92.35	—

Amino-acid sequence (240 residues)

MPVSKCPKKS ESLWKGWDRK AQRNGLRSQV YAVNGDYYVG EWKDNVKHGK GTQVWKKKGA IYEGDWKFGK RDGYGTLSLP DQQTGKCRRV YSGWWKGDKK SGYGIQFFGP KEYYEGDWCG SQRSGWGRMY YSNGDIYEGQ WENDKPNGEG MLRLKNGNRY EGCWERGMKN GAGRFFHLDH GQLFEGFWVD NMAKCGTMID FGRDEAPEPT QFPIPEVKIL DPDGVLAEAL AMFRKTEEGD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards