Protein cornichon homolog 2 (CNIH2)

About Protein cornichon homolog 2

Protein cornichon homolog 2 (CNIH2) is a protein from Homo sapiens identified by UniProt accession Q6PI25, 160 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Protein cornichon homolog 2
UniProt accession	Q6PI25
Gene	CNIH2
Organism	Homo sapiens
Length	160 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
urate measurement · score 0.19
cutaneous melanoma · score 0.14
body fat percentage · score 0.12
lean body mass · score 0.11
gout · score 0.11
fat body mass · score 0.09
insomnia measurement · score 0.08
high density lipoprotein cholesterol measurement · score 0.07
mathematical ability · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PI25-F1	alphafold	PREDICTED	87.41	—

Amino-acid sequence (160 residues)

MAFTFAAFCY MLTLVLCASL IFFVIWHIIA FDELRTDFKN PIDQGNPARA RERLKNIERI CCLLRKLVVP EYSIHGLFCL MFLCAAEWVT LGLNIPLLFY HLWRYFHRPA DGSEVMYDAV SIMNADILNY CQKESWCKLA FYLLSFFYYL YSMVYTLVSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards