BTB/POZ domain-containing protein KCTD18 (KCTD18)

About BTB/POZ domain-containing protein KCTD18

BTB/POZ domain-containing protein KCTD18 (KCTD18) is a protein from Homo sapiens identified by UniProt accession Q6PI47, 426 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	BTB/POZ domain-containing protein KCTD18
UniProt accession	Q6PI47
Gene	KCTD18
Organism	Homo sapiens
Length	426 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PI47-F1	alphafold	PREDICTED	59.60	—

Amino-acid sequence (426 residues)

MEGHKAEEEV LDVLRLNVGG CIYTARRESL CRFKDSMLAS MFSGRFPLKT DESGACVIDR DGRLFKYLLD YLHGEVQIPT DEQTRIALQE EADYFGIPYP YSLSDHLANE METYSLRSNI ELKKALTDFC DSYGLVCNKP TVWVLHYLNT SGASCESRII GVYATKTDGT DAIEKQLGGR IHSKGIFKRE AGNNVQYIWS YYSVAELKKM MDAFDAWEGK GVSYWRVPHE LIECWTLEER PLLGSLRHMA PIRKRRLITF NEADESVNYK TGPKPVRFLG PSTSTQIKVK NSASVTVSPA SAIQTSAGAT ANRFQSGSRR KAAQRSAPSR ATALVGTGAP GHPQASPGAA SAENGGTHLP PAKVLLSDKK PTPQRVIKLK RTPLCATAPC LPSPTATRQA NSLKPLPGEA ARALGVRTEN GKNKGN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards