About Leukocyte immunoglobulin-like receptor subfamily A member 6
Leukocyte immunoglobulin-like receptor subfamily A member 6 (LILRA6) is a protein
from Homo sapiens identified by UniProt accession
Q6PI73, 481 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 6 |
|---|
| UniProt accession | Q6PI73 |
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| Gene | LILRA6 |
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| Organism | Homo sapiens |
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| Length | 481 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (84)
Diseases linked to this target (Open Targets).
- inflammatory bowel disease · score 0.14
- blood protein measurement · score 0.12
- creatine kinase measurement · score 0.09
- response to statin · score 0.09
- birth weight · score 0.07
- body height · score 0.07
- common variable immunodeficiency · score 0.06
- Chronic mucocutaneous candidosis · score 0.06
- isolated agammaglobulinemia · score 0.06
- classic Hodgkin lymphoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PI73-F1 | alphafold | PREDICTED | 85.32 | — |
Amino-acid sequence (481 residues)
MTPALTALLC LGLSLGPRTR VQAGPFPKPT LWAEPGSVIS WGSPVTIWCQ GSLEAQEYQL DKEGSPEPLD RNNPLEPKNK ARFSIPSMTQ HHAGRYRCHY YSSAGWSEPS DPLELVMTGF YNKPTLSALP SPVVASGGNM TLRCGSQKGY HHFVLMKEGE HQLPRTLDSQ QLHSGGFQAL FPVGPVTPSH RWRFTCYYYY TNTPRVWSHP SDPLEILPSG VSRKPSLLTL QGPVLAPGQS LTLQCGSDVG YDRFVLYKEG ERDFLQRPGQ QPQAGLSQAN FTLGPVSPSH GGQYRCYGAH NLSSEWSAPS DPLNILMAGQ IYDTVSLSAQ PGPTVASGEN VTLLCQSRGY FDTFLLTKEG AAHPPLRLRS MYGAHKYQAE FPMSPVTSAH AGTYRCYGSY SSNPHLLSFP SEPLELMVSG HSGGSSLPPT GPPSTPASHA KDYTVENLIR MGMAGLVLVF LGILLFEAQH SQRNPQDAAG R
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