Transmembrane protein 65 (TMEM65)

Homo sapiens — UniProt Q6PI78

Gene: TMEM65Homo sapiensSwissProt reviewed

About Transmembrane protein 65

Transmembrane protein 65 (TMEM65) is a protein from Homo sapiens identified by UniProt accession Q6PI78, 240 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein nameTransmembrane protein 65
UniProt accessionQ6PI78
GeneTMEM65
OrganismHomo sapiens
Length240 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6PI78-F1alphafoldPREDICTED72.35—

Amino-acid sequence (240 residues)

MSRLLPLLRS RTARSLRPGP AAAAAPRPPS WCCCGRGLLA LAPPGGLPGG PRRLGTHPKK EPMEALNTAQ GARDFIYSLH STERSCLLKE LHRFESIAIA QEKLEAPPPT PGQLRYVFIH NAIPFIGFGF LDNAIMIVAG THIEMSIGII LGISTMAAAA LGNLVSDLAG LGLAGYVEAL ASRLGLSIPD LTPKQVDMWQ TRLSTHLGKA VGVTIGCILG MFPLIFFGGG EEDEKLETKS

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Quick facts

UniProtQ6PI78
GeneTMEM65
OrganismHomo sapiens
Length240
Binders0
Diseases37
View on UniProt