About Tetratricopeptide repeat protein 33
Tetratricopeptide repeat protein 33 (TTC33) is a protein
from Homo sapiens identified by UniProt accession
Q6PID6, 262 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Tetratricopeptide repeat protein 33 |
|---|
| UniProt accession | Q6PID6 |
|---|
| Gene | TTC33 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 262 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- gastric carcinoma · score 0.37
- Crohn's disease · score 0.25
- erythrocyte count · score 0.23
- gastric cardia carcinoma · score 0.23
- ulcerative colitis · score 0.22
- mean corpuscular hemoglobin concentration · score 0.21
- inflammatory bowel disease · score 0.19
- psoriasis · score 0.18
- multiple sclerosis · score 0.18
- hemoglobin measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PID6-F1 | alphafold | PREDICTED | 79.84 | — |
Amino-acid sequence (262 residues)
MASFGWKRKI GEKVSKVTSQ QFEAEAADEK DVVDNDEGNW LHAIKRRKEI LLEGCAEKSK QLKDEGASLA ENKRYREAIQ KWDEALQLTP NDATLYEMKS QVLMSLHEMF PAVHAAEMAV QQNPHSWESW QTLGRAQLGL GEIILAIRSF QVALHIYPMN PEIWKEDLSW ARTLQEQQKV AQRIKKSEAP AEVTHFSPKS IPDYDFESDE IVAVCAAIAE KEKTVSANKT MVIVSASGAI ETVTEKEDGA TPPDGSVFIK AR
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