About Kv channel-interacting protein 4
Kv channel-interacting protein 4 (KCNIP4) is a protein
from Homo sapiens identified by UniProt accession
Q6PIL6, 250 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Kv channel-interacting protein 4 |
|---|
| UniProt accession | Q6PIL6 |
|---|
| Gene | KCNIP4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 250 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.45
- mathematical ability · score 0.45
- body fat percentage · score 0.40
- body height · score 0.37
- cognitive function measurement · score 0.37
- appendicular lean mass · score 0.36
- testosterone measurement · score 0.33
- neuroticism measurement · score 0.32
- PHF-tau measurement · score 0.28
- diffuse plaque measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PIL6-F1 | alphafold | PREDICTED | 69.84 | — |
Amino-acid sequence (250 residues)
MNVRRVESIS AQLEEASSTG GFLYAQNSTK RSIKERLMKL LPCSAAKTSS PAIQNSVEDE LEMATVRHRP EALELLEAQS KFTKKELQIL YRGFKNECPS GVVNEETFKE IYSQFFPQGD STTYAHFLFN AFDTDHNGAV SFEDFIKGLS ILLRGTVQEK LNWAFNLYDI NKDGYITKEE MLDIMKAIYD MMGKCTYPVL KEDAPRQHVE TFFQKMDKNK DGVVTIDEFI ESCQKDENIM RSMQLFENVI
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