About Potassium voltage-gated channel subfamily V member 1
Potassium voltage-gated channel subfamily V member 1 (KCNV1) is a protein
from Homo sapiens identified by UniProt accession
Q6PIU1, 500 residues long.
MolForge cross-references it against 0 known binders and
352 disease associations.
Target properties
| Protein name | Potassium voltage-gated channel subfamily V member 1 |
|---|
| UniProt accession | Q6PIU1 |
|---|
| Gene | KCNV1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 500 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (352)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.59
- Myasthenia gravis · score 0.57
- small cell carcinoma · score 0.46
- Muscle weakness · score 0.46
- secondary progressive multiple sclerosis · score 0.43
- anterior ischemic optic neuropathy · score 0.37
- primary progressive multiple sclerosis · score 0.37
- transverse myelitis · score 0.37
- atrial flutter · score 0.35
- atrial fibrillation · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q6PIU1-F1 | alphafold | PREDICTED | 78.52 | — |
Amino-acid sequence (500 residues)
MPSSGRALLD SPLDSGSLTS LDSSVFCSEG EGEPLALGDC FTVNVGGSRF VLSQQALSCF PHTRLGKLAV VVASYRRPGA LAAVPSPLEL CDDANPVDNE YFFDRSSQAF RYVLHYYRTG RLHVMEQLCA LSFLQEIQYW GIDELSIDSC CRDRYFRRKE LSETLDFKKD TEDQESQHES EQDFSQGPCP TVRQKLWNIL EKPGSSTAAR IFGVISIIFV VVSIINMALM SAELSWLDLQ LLEILEYVCI SWFTGEFVLR FLCVRDRCRF LRKVPNIIDL LAILPFYITL LVESLSGSQT TQELENVGRI VQVLRLLRAL RMLKLGRHST GLRSLGMTIT QCYEEVGLLL LFLSVGISIF STVEYFAEQS IPDTTFTSVP CAWWWATTSM TTVGYGDIRP DTTTGKIVAF MCILSGILVL ALPIAIINDR FSACYFTLKL KEAAVRQREA LKKLTKNIAT DSYISVNLRD VYARSIMEML RLKGRERAST RSSGGDDFWF
Explore Potassium voltage-gated channel subfamily V member 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets