Neutral cholesterol ester hydrolase 1 (NCEH1)

About Neutral cholesterol ester hydrolase 1

Neutral cholesterol ester hydrolase 1 (NCEH1) is a protein from Homo sapiens identified by UniProt accession Q6PIU2, 408 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein name	Neutral cholesterol ester hydrolase 1
UniProt accession	Q6PIU2
Gene	NCEH1
Organism	Homo sapiens
Length	408 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6PIU2-F1	alphafold	PREDICTED	96.29	—

Amino-acid sequence (408 residues)

MRSSCVLLTA LVALAAYYVY IPLPGSVSDP WKLMLLDATF RGAQQVSNLI HYLGLSHHLL ALNFIIVSFG KKSAWSSAQV KVTDTDFDGV EVRVFEGPPK PEEPLKRSVV YIHGGGWALA SAKIRYYDEL CTAMAEELNA VIVSIEYRLV PKVYFPEQIH DVVRATKYFL KPEVLQKYMV DPGRICISGD SAGGNLAAAL GQQFTQDASL KNKLKLQALI YPVLQALDFN TPSYQQNVNT PILPRYVMVK YWVDYFKGNY DFVQAMIVNN HTSLDVEEAA AVRARLNWTS LLPASFTKNY KPVVQTTGNA RIVQELPQLL DARSAPLIAD QAVLQLLPKT YILTCEHDVL RDDGIMYAKR LESAGVEVTL DHFEDGFHGC MIFTSWPTNF SVGIRTRNSY IKWLDQNL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards